N
Dr. Naman Aggarwal · Manipal Hospital
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Urgent evaluation

Blood in Urine

Haematuria · Cystoscopy

A urologic cancer is found in about 1 in 5 people with visible blood in the urine, making evaluation essential even after a single episode (NIH/Cleveland Clinic).

Haematuria means blood is present in the urine — sometimes visible as pink, red, or cola-coloured urine, and sometimes detectable only under a microscope or dipstick test. It's a symptom, not a disease in itself, and the underlying causes range from harmless to serious.

Microscopic (invisible) blood in urine affects an estimated 6.5% of the general population, more common in older men, with some studies reporting rates as high as 21% (NIH).

Causes & risk factors

  • Urinary tract or kidney infection
  • Kidney or bladder stones
  • Enlarged prostate (BPH)
  • Vigorous exercise (usually harmless and temporary)
  • Chronic kidney disease
  • Urologic cancers — found in about 5% of microscopic and 20% of visible haematuria cases (NIH/Cleveland Clinic)

Symptoms to watch for

  • Pink, red, or cola-coloured urine
  • Blood clots in the urine
  • Pain or burning during urination, if infection-related
  • Flank or lower back pain
  • Painless visible blood in urine must be evaluated promptly to rule out cancer; fever, chills, or inability to urinate are also urgent

How it's diagnosed

  • Urinalysis and urine culture
  • Urine cytology (checks for abnormal cells)
  • Cystoscopy — a camera scope examines the bladder and urethra directly; the key test for unexplained or visible blood
  • Imaging: CT urogram, ultrasound, or MRI

Treatment options

  • Antibiotics: if the cause is a urinary infection.
  • Prostate medication: alpha-blockers or 5-alpha reductase inhibitors if BPH is the cause.
  • Stone treatment: as above (SWL, ureteroscopy, RIRS or PCNL) if a stone is responsible.
  • Cancer-specific therapy: surgery, radiation, or other treatment if a tumour is found.
  • Observation: mild, exercise-induced haematuria often needs no treatment at all.

Outlook & prevention

Haematuria itself usually isn't life-threatening, but the underlying cause determines the outcome — so timely evaluation matters, especially for painless visible blood. A urologic cancer is found in roughly 1 in 5 people who have visible blood in urine, which is why full evaluation should never be skipped, even after a single episode.

When to see a doctor
  • Any visible blood in the urine, even a single, painless episode
  • Blood in urine together with fever, flank pain, or difficulty urinating
  • Microscopic blood found incidentally on a routine urine test

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